Advances in Material Modification with Smart Functional Polymers for Combating Biofilms in Biomedical Applications

Biofilms as living microorganism communities are found anywhere, and for the healthcare sector, these constitute a threat allied mechanism health-associated or nosocomial infections. This review states basis of biofilms their formation. It focuses on relevance biomedical generalities, major advances in modified new synthesized materials to prevent control biofilm formation biomedicine. Biofilm is conceptualized an aggregate cells highly communicated extracellular matrix, which obeys molecular genetic basis. The offers protection microorganisms from unfavorable environmental conditions. most frequent genera forming reported infections Staphylococcus spp., Escherichia Candida spp. implants, heart valves, catheters, medical devices, prostheses. During last decade, have been commonly related deaths Europe, United States, Mexico. Smart, functional polymers capable responding diverse stimuli. These represent strategy fight against through modification synthesis materials. Polypropylene poly-N-isopropyl acrylamide were used enough literature analysis performed. Even smart serve delivery systems other substances, such antibiotics, control.